Metazoan complexes |
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Details of ALDOA gene in Homo sapiens
IDs | |||||||||
---|---|---|---|---|---|---|---|---|---|
Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
| ALDOA | ALDA | P04075 | ALDOA_HUMAN | 226 | ENSG00000149925 | Fructose-bisphosphate aldolase A | SPROT |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | OMIM id | ||||||||
Glycogen storage disease 12 (GSD12) [MIM:611881]: A metabolic disorder associated with increased hepatic glycogen and hemolytic anemia. It may lead to myopathy with exercise intolerance and rhabdomyolysis. Note=The disease is caused by mutations affecting the gene represented in this entry. | 611881 |
Phenotypes
Abnormal axial skeleton morphology, Abnormal hair pattern, Abnormality of blood and blood-forming tissues, Abnormality of body height, Abnormality of erythrocytes, Abnormality of head and neck, Abnormality of higher mental function, Abnormality of metabolism/homeostasis, Abnormality of skeletal morphology, Abnormality of skin adnexa, Abnormality of the abdomen, Abnormality of the abdominal organs, Abnormality of the biliary system, Abnormality of the central nervous system, Abnormality of the cervical spine, Abnormality of the endocrine system, Abnormality of the eye, Abnormality of the eyelid, Abnormality of the face, Abnormality of the gallbladder, Abnormality of the hair, Abnormality of the hairline, Abnormality of the head, Abnormality of the immune system, Abnormality of the integument, Abnormality of the liver, Abnormality of the lymphatic system, Abnormality of the neck, Abnormality of the nervous system, Abnormality of the ocular region, Abnormality of the periorbital region, Abnormality of the scalp, Abnormality of the scalp hair, Abnormality of the skeletal system, Abnormality of the skin, Abnormality of the spleen, Abnormality of the vertebral column, All, Anemia, Anemia due to reduced life span of red cells, Anemia of inadequate production, Autosomal recessive inheritance, Cholecystitis, Cholelithiasis, Cholestasis, Cognitive impairment, Congenital abnormal hair pattern, Congenital hemolytic anemia, Delayed puberty, Dermatological manifestations of systemic disorders, Epicanthus, Generalized abnormality of skin, Growth abnormality, Growth delay, Hemolytic anemia, Intellectual disability, Jaundice, Low posterior hairline, Mode of inheritance, Normochromic anemia, Normocytic anemia, Phenotypic abnormality, Ptosis, Puberty and gonadal disorders, Short neck, Short stature, Splenomegaly, Visceromegaly.
Orthologs in other species | |||||||||
---|---|---|---|---|---|---|---|---|---|
M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
Aldoa | Ald | aldo-1 | Sp-Aldoaa... |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
---|---|---|---|---|---|---|---|---|---|
ARHGDIA | ALDOA | 0.277576899 | ARHGDIA | ALDOA | cpx3; cpx49 | no | yes | no | Known |
ALDOC | ALDOA | 0.455858882 | ALDOC | ALDOA | cpx119; cpx49; cpx118 | no | yes | no | Known |
GPX4 | ALDOA | 0.073053362 | GPX4 | ALDOA | cpx3 | no | no | no | Novel |
ACO2 | ALDOA | 0.579521549 | ACO2 | ALDOA | cpx49; cpx119 | no | yes | no | Known |
GPD1L | ALDOA | 0.990673066 | GPD1L | ALDOA | cpx49; cpx119 | no | yes | no | Known |
IMPA2 | ALDOA | 0.185113833 | IMPA2 | ALDOA | cpx49 | no | no | no | Novel |
TAGLN | ALDOA | 0.647427199 | TAGLN | ALDOA | cpx3 | no | yes | no | Known |
SUMO3 | ALDOA | 0.049208388 | SUMO3 | ALDOA | cpx3 | no | no | no | Novel |
PKM | ALDOA | 0.102610786 | PKM | ALDOA | cpx772 | no | no | no | Novel |
MYH7B | ALDOA | 0.609887682 | MYH7B | ALDOA | cpx49 | no | no | no | Novel |
ISYNA1 | ALDOA | 0.918060215 | ISYNA1 | ALDOA | cpx772 | no | yes | no | Known |
HSD17B10 | ALDOA | 0.317764025 | HSD17B10 | ALDOA | cpx3 | no | yes | no | Known |
STIP1 | ALDOA | 0.064309579 | STIP1 | ALDOA | cpx3 | no | no | no | Novel |
TAGLN2 | ALDOA | 0.947374167 | TAGLN2 | ALDOA | cpx3 | no | yes | no | Known |
ALDOA | HSPE1 | 0.564031281 | ALDOA | HSPE1 | cpx3 | no | no | no | Novel |
ALDOA | DUT | 0.241874561 | ALDOA | DUT | cpx3 | no | no | no | Novel |
ALDOA | FABP5 | 0.08989527 | ALDOA | FABP5 | cpx3 | no | no | no | Novel |
ALDOA | FKBP7 | 0.231584042 | ALDOA | FKBP7 | cpx119; cpx118 | no | yes | no | Known |
ALDOA | FH | 0.670232004 | ALDOA | FH | cpx443 | no | no | no | Novel |
ALDOA | GAPDH | 0.164493549 | ALDOA | GAPDH | cpx828 | no | yes | no | Known |
ALDOA | CKMT2 | 0.287882322 | ALDOA | CKMT2 | cpx118; cpx119 | no | yes | no | Known |
ALDOA | CKMT1B | 0.299484513 | ALDOA | CKMT1B | cpx49 | no | yes | no | Known |
ALDOA | GLO1 | 0.115902026 | ALDOA | GLO1 | cpx49 | no | yes | no | Known |
ALDOA | PGAM2 | 0.268694474 | ALDOA | PGAM2 | cpx118 | no | yes | no | Known |
ALDOA | PRDX1 | 0.069550967 | ALDOA | PRDX1 | cpx929 | no | no | no | Novel |
ALDOA | ACAA2 | 0.352605913 | ALDOA | ACAA2 | cpx3 | no | no | no | Novel |
ALDOA | UCHL3 | 0.062095405 | ALDOA | UCHL3 | cpx3 | no | yes | no | Known |
ALDOA | UMPS | 0.166800794 | ALDOA | UMPS | cpx118 | no | no | no | Novel |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
---|---|---|---|---|
ALDOA | CKB | 0.5 | ALDOA | CKB |
CFL1 | ALDOA | 0.082498032 | CFL1 | ALDOA |
TRAP1 | ALDOA | 0.172118634 | TRAP1 | ALDOA |
ALDOA | ACTN4 | 0.102400852 | ALDOA | ACTN4 |
LMAN1 | ALDOA | 0.079036316 | LMAN1 | ALDOA |
MAP2K7 | ALDOA | 0.075295347 | MAP2K7 | ALDOA |
ALDOA | LDHA | 0.087671975 | ALDOA | LDHA |
ECHS1 | ALDOA | 0.117328036 | ECHS1 | ALDOA |
ADI1 | ALDOA | 0.10968849 | ADI1 | ALDOA |
ALDOA | SOD2 | 0.152409172 | ALDOA | SOD2 |
TKT | ALDOA | 0.418437734 | TKT | ALDOA |
ASS1 | ALDOA | 0.117310896 | ASS1 | ALDOA |
ALDOA | ATP5J | 0.093066396 | ALDOA | ATP5J |
ALDOA | NDUFS4 | 0.125819271 | ALDOA | NDUFS4 |
ALDOA | LTA4H | 0.118572605 | ALDOA | LTA4H |
CDK2 | ALDOA | 0.31378362 | CDK2 | ALDOA |
SUMO2 | ALDOA | 0.112220624 | SUMO2 | ALDOA |
ALDOA | KCNAB2 | 0.113095385 | ALDOA | KCNAB2 |
RP1-241P17.4 | ALDOA | 0.071667656 | RP1-241P17.4 | ALDOA |
PGK1 | ALDOA | 0.470536 | PGK1 | ALDOA |
ALDOA | PREP | 0.072162184 | ALDOA | PREP |
FKBP2 | ALDOA | 0.296486006 | FKBP2 | ALDOA |
ALDOA | ENO1 | 0.115811325 | ALDOA | ENO1 |
ALDOA | SUMO4 | 0.082875389 | ALDOA | SUMO4 |
COX4I1 | ALDOA | 0.10491649 | COX4I1 | ALDOA |
ALDOA | TALDO1 | 0.126215339 | ALDOA | TALDO1 |