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Details of ATF1 gene in Homo sapiens
IDs |
|---|
| Link outs |
Gene Name |
Alias |
Uniprot ID |
SwissProt ID |
NCBI gene ID |
ENSEMBL ID |
Description |
Source |
|
| ATF1 | --- | P18846 | ATF1_HUMAN | 466
| ENSG00000123268
| Cyclic AMP-dependent transcription factor ATF-1 | SPROT |
Disease |
|---|
| Disease |
OMIM id |
| Angiomatoid fibrous histiocytoma (AFH) [MIM:612160]: A distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth. Characteristic microscopic features include lobulated sheets of histiocyte-like cells intimately associated with areas of hemorrhage and cystic pseudovascular spaces, as well as a striking cuffing of inflammatory cells, mimicking a lymph node metastasis. Note=The gene represented in this entry may be involved in disease pathogenesis. Chromosomal aberrations involving ATF1 are found in patients with angiomatoid fibrous histiocytoma. Translocation t(1216)(q13p11.2) with FUS generates a chimeric ATF1/FUS protein. Translocation t(1222)(q13q12) with EWSR1 generates a chimeric ATF1/EWSR1 protein. |
612160 |
Orthologs in other species |
|---|
| M. musculus |
D. melonogaster |
C. elegans |
S. purpuratus |
| Atf1 | CrebB-17A | --- | Sp-Creb |
