Metazoan complexes |
|
Emili & Marcotte labs |
- Home
-
-
-
-
-
-
-
- Download
- Help
- Contact
Details of CCT5 gene in Homo sapiens
IDs | |||||||||
---|---|---|---|---|---|---|---|---|---|
Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
| CCT5 | CCTE,KIAA0098 | P48643 | TCPE_HUMAN | 22948 | ENSG00000150753 | T-complex protein 1 subunit epsilon | SPROT |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | OMIM id | ||||||||
Hereditary sensory neuropathy, autosomal recessive, with spastic paraplegia (HSNSP) [MIM:256840]: A disease characterized by spastic paraplegia and progressive distal sensory neuropathy leading to mutilating ulcerations of the upper and lower limbs. Note=The disease is caused by mutations affecting the gene represented in this entry. | 256840 |
Phenotypes
Abnormal appendicular skeleton morphology, Abnormality of central motor function, Abnormality of limb bone morphology, Abnormality of metabolism/homeostasis, Abnormality of movement, Abnormality of muscle morphology, Abnormality of pyramidal motor function, Abnormality of skeletal morphology, Abnormality of skeletal physiology, Abnormality of the central nervous system, Abnormality of the foot, Abnormality of the lower limb, Abnormality of the musculature, Abnormality of the nervous system, Abnormality of the peripheral nervous system, Abnormality of the skeletal system, Abnormality of the spinal cord, Age of onset, All, Amyotrophy, Atrophy/Degeneration affecting the central nervous system, Atrophy/Degeneration involving the spinal cord, Atrophy of the spinal cord, Autosomal recessive inheritance, Babinski sign, Clonus, Distal amyotrophy, Distal sensory impairment, Distal sensory impairment of all modalities, Distal sensory loss of all modalities, Hyperreflexia, Hypertonia, Infantile onset, Juvenile onset, Lower limb spasticity, Mode of inheritance, Morphological abnormality of the central nervous system, Onset, Onset and clinical course, Osteomyelitis, Pace of progression, Paralysis due to lesions of the principle motor tracts, Paraplegia, Paraplegia/paraparesis, Peripheral axonal degeneration, Peripheral axonal neuropathy, Peripheral neuropathy, Phenotypic abnormality, Rapidly progressive, Sensory impairment, Sensory neuropathy, Spastic gait, Spasticity, Spastic paraplegia.
Orthologs in other species | |||||||||
---|---|---|---|---|---|---|---|---|---|
M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
Cct5 | Cct5 | cct-5 | Sp-Cct5 |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
---|---|---|---|---|---|---|---|---|---|
CCT5 | TCP1 | 1 | CCT5 | TCP1 | cpx28 | yes | yes | yes | Known |
CCT5 | CCT2 | 1 | CCT5 | CCT2 | cpx28 | yes | yes | no | Known |
CCT5 | CCT4 | 1 | CCT5 | CCT4 | cpx28 | yes | yes | no | Known |
CCT5 | CCT3 | 1 | CCT5 | CCT3 | cpx28 | yes | yes | yes | Known |
CCT5 | CCT7 | 1 | CCT5 | CCT7 | cpx28 | yes | yes | no | Known |
CCT5 | CCT8 | 1 | CCT5 | CCT8 | cpx28 | yes | yes | no | Known |
CCT5 | CCT6B | 1 | CCT5 | CCT6B | cpx28 | no | yes | yes | Known |
CCT5 | CCT6A | 1 | CCT5 | CCT6A | cpx28 | yes | yes | yes | Known |