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Metazoan complexes |
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Details of CDK12 gene in Homo sapiens
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
|
| CDK12 | CRK7,CRKRS,KIAA0904 | Q9NYV4 | CDK12_HUMAN | 51755 | ENSG00000167258 | Cyclin-dependent kinase 12 | SPROT | |
Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | OMIM id | ||||||||
| Note=Chromosomal aberrations involving CDK12 may be a cause gastric cancer. Deletions within 17q12 region producing fusion transcripts with ERBB2, leading to CDK12-ERBB2 fusion leading to trunctated CDK12 protein not in-frame with ERBB2. | --- | ||||||||
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
| Cdk12 | Cdk12 | cdtl-7 | Sp-Cdc2l5 | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| CCNK | CDK12 | 0.999998683 | CCNK | CDK12 | cpx352 | no | yes | no | Known |
| MAP4K4 | CDK12 | 0.122428178 | MAP4K4 | CDK12 | cpx352 | no | no | no | Novel |