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Metazoan complexes |
Emili & Marcotte labs |
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Details of CUL3 gene in Homo sapiens
IDs | |||||||||
---|---|---|---|---|---|---|---|---|---|
Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
| CUL3 | KIAA0617 | Q13618 | CUL3_HUMAN | 8452 | ENSG00000036257 | Cullin-3 | SPROT |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | OMIM id | ||||||||
Pseudohypoaldosteronism 2E (PHA2E) [MIM:614496]: An autosomal dominant disorder characterized by severe hypertension, hyperkalemia, hyperchloremia, hyperchloremic metabolic acidosis, and correction of physiologic abnormalities by thiazide diuretics. Note=The disease is caused by mutations affecting the gene represented in this entry. | 614496 |
Orthologs in other species | |||||||||
---|---|---|---|---|---|---|---|---|---|
M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
Cul3 | Cul-3 | cul-3 | Sp-Cul3 |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
---|---|---|---|---|---|---|---|---|---|
CUL3 | CUL1 | 0.440912309 | CUL3 | CUL1 | cpx207 | yes | yes | no | Known |
CUL3 | CUL2 | 0.183606607 | CUL3 | CUL2 | cpx207 | yes | yes | no | Known |
CUL3 | KATNA1 | 0.160126478 | CUL3 | KATNA1 | cpx207 | no | yes | no | Known |