Metazoan complexes |
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Emili & Marcotte labs |
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Details of EPS15 gene in Homo sapiens
IDs | |||||||||
---|---|---|---|---|---|---|---|---|---|
Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
| EPS15 | AF1P | P42566 | EPS15_HUMAN | 2060 | ENSG00000085832 | Epidermal growth factor receptor substrate 15 | SPROT |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | OMIM id | ||||||||
Note=A chromosomal aberration involving EPS15 is found in acute leukemias. Translocation t(111)(p32q23) with MLL/HRX. The result is a rogue activator protein. | --- |
Orthologs in other species | |||||||||
---|---|---|---|---|---|---|---|---|---|
M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
Eps15 | Eps-15 | ehs-1 | Sp-Eps15l1l |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
---|---|---|---|---|---|---|---|---|---|
ITSN2 | EPS15 | 0.217267861 | ITSN2 | EPS15 | cpx327 | no | yes | no | Known |
ITSN1 | EPS15 | 0.309915641 | ITSN1 | EPS15 | cpx327 | no | yes | no | Known |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
---|---|---|---|---|