|
Metazoan complexes |
Emili & Marcotte labs |
Please wait while page loads....
- Home
-
H.sapiens
-
M.musculus
-
D.melanogaster
-
C.elegans
-
S.purpuratus
-
Conserved map
-
PPI Projections
- Download
- Help
- Contact
Details of EXOSC3 gene in Homo sapiens
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
|
| EXOSC3 | RRP40 | Q9NQT5 | EXOS3_HUMAN | 51010 | ENSG00000107371 | Exosome complex component RRP40 | SPROT | |
Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | OMIM id | ||||||||
| Pontocerebellar hypoplasia 1B (PCH1B) [MIM:614678]: A severe autosomal recessive neurologic disorder characterized by a combination of cerebellar and spinal motor neuron degeneration beginning at birth. There is diffuse muscle weakness, progressive microcephaly, global developmental delay, and brainstem involvement. Note=The disease is caused by mutations affecting the gene represented in this entry. | 614678 | ||||||||
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
| Exosc3 | Rrp40 | exos-3 | Sp-Exosc3... | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| EXOSC3 | EXOSC1 | 1 | EXOSC3 | EXOSC1 | cpx19 | yes | yes | no | Known |
| EXOSC2 | EXOSC3 | 1 | EXOSC2 | EXOSC3 | cpx19 | yes | yes | yes | Known |
| MPHOSPH6 | EXOSC3 | 1 | MPHOSPH6 | EXOSC3 | cpx19 | no | yes | no | Known |
| EXOSC5 | EXOSC3 | 1 | EXOSC5 | EXOSC3 | cpx19 | yes | yes | yes | Known |
| EXOSC10 | EXOSC3 | 1 | EXOSC10 | EXOSC3 | cpx19 | yes | yes | yes | Known |
| EXOSC4 | EXOSC3 | 1 | EXOSC4 | EXOSC3 | cpx19 | yes | yes | yes | Known |
| EXOSC7 | EXOSC3 | 1 | EXOSC7 | EXOSC3 | cpx19 | yes | yes | no | Known |
| EXOSC9 | EXOSC3 | 1 | EXOSC9 | EXOSC3 | cpx19 | yes | yes | yes | Known |
| EXOSC3 | EXOSC6 | 1 | EXOSC3 | EXOSC6 | cpx19 | yes | yes | no | Known |