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Metazoan complexes |
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Details of GLRX5 gene in Homo sapiens
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
|
| GLRX5 | C14orf87 | Q86SX6 | GLRX5_HUMAN | 51218 | ENSG00000182512 | Glutaredoxin-related protein 5, mitochondrial | SPROT | |
Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | OMIM id | ||||||||
| Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive (PRARSA) [MIM:205950]: A form of sideroblastic anemia not responsive to pyridoxine. Sideroblastic anemia is characterized by anemia of varying severity, hypochromic peripheral erythrocytes, systemic iron overload secondary to chronic ineffective erythropoiesis, and the presence of bone marrow ringed sideroblasts. Sideroblasts are characterized by iron-loaded mitochondria clustered around the nucleus. Note=The disease is caused by mutations affecting the gene represented in this entry. | 205950 | ||||||||
Phenotypes
Abnormality of blood and blood-forming tissues, Abnormality of cation homeostasis, Abnormality of erythrocytes, Abnormality of ion homeostasis, Abnormality of iron homeostasis, Abnormality of metabolism/homeostasis, Abnormality of transition element cation homeostasis, Age of onset, All, Anemia, Autosomal recessive inheritance, Heterogeneous, Increased serum ferritin, Infantile onset, Mode of inheritance, Onset, Onset and clinical course, Phenotypic abnormality.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
| Glrx5 | CG14407 | glrx-5 | Sp-Glrx5... | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| GLRX5 | BOLA1 | 0.129817792 | GLRX5 | BOLA1 | cpx359 | no | no | no | Novel |
| GLRX5 | BOLA3 | 0.116145593 | GLRX5 | BOLA3 | cpx359 | no | no | no | Novel |
| GLRX5 | GLOD4 | 0.133806414 | GLRX5 | GLOD4 | cpx64 | no | no | no | Novel |
| GLRX5 | TXN | 0.293037309 | GLRX5 | TXN | cpx64 | no | no | no | Novel |