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Metazoan complexes |
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Details of GMPS gene in Homo sapiens
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
|
| GMPS | --- | P49915 | GUAA_HUMAN | 8833 | ENSG00000163655 | GMP synthase [glutamine-hydrolyzing] | SPROT | |
Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | OMIM id | ||||||||
| Note=A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with MLL. | --- | ||||||||
Phenotypes
Abnormality of blood and blood-forming tissues, Abnormality of cellular immune system, Abnormality of leukocytes, Abnormality of the immune system, Acute leukemia, Acute myeloid leukemia, Age of onset, All, Autosomal dominant inheritance, Familial acute myelogenous leukemia, Hematological neoplasm, Infantile onset, Leukemia, Mode of inheritance, Neoplasm, Neoplasm by anatomical site, Onset, Onset and clinical course, Phenotypic abnormality.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
| Gmps | bur | gmps-1 | Sp-Gmps | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| GMPS | IMPDH1 | 0.260006409 | GMPS | IMPDH1 | cpx97 | no | no | no | Novel |
| GMPS | IMPDH2 | 0.088851674 | GMPS | IMPDH2 | cpx97 | no | no | no | Novel |
| GMPS | CTPS1 | 0.133924044 | GMPS | CTPS1 | cpx97 | no | no | no | Novel |
| GMPS | USP7 | 0.283673366 | GMPS | USP7 | cpx97 | no | yes | no | Known |