|
Metazoan complexes |
Emili & Marcotte labs |
Please wait while page loads....
- Home
-
H.sapiens
-
M.musculus
-
D.melanogaster
-
C.elegans
-
S.purpuratus
-
Conserved map
-
PPI Projections
- Download
- Help
- Contact
Details of HEATR2 gene in Homo sapiens
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
|
| HEATR2 | --- | Q86Y56 | HEAT2_HUMAN | 54919 | ENSG00000164818 | HEAT repeat-containing protein 2 | SPROT | |
Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | OMIM id | ||||||||
| Primary ciliary dyskinesia 18 (CILD18) [MIM:614874]: A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Note=The disease is caused by mutations affecting the gene represented in this entry. | 614874 | ||||||||
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
| Heatr2 | CG31320 | --- | Sp-Heatr2 | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| MAPK1 | HEATR2 | 0.159647815 | MAPK1 | HEATR2 | cpx202 | no | no | no | Novel |
| HEATR2 | RRM2 | 0.158763679 | HEATR2 | RRM2 | cpx202 | no | no | no | Novel |
| HEATR2 | XPO6 | 0.124793935 | HEATR2 | XPO6 | cpx202 | no | no | no | Novel |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
|---|---|---|---|---|
| ITPK1 | HEATR2 | 0.116918711 | ITPK1 | HEATR2 |
| PPP2R5D | HEATR2 | 0.13029713 | PPP2R5D | HEATR2 |
| PTPRF | HEATR2 | 0.081995654 | PTPRF | HEATR2 |
| DCUN1D1 | HEATR2 | 0.070310973 | DCUN1D1 | HEATR2 |
| RAD23B | HEATR2 | 0.095691929 | RAD23B | HEATR2 |
| HEATR2 | ADRBK1 | 0.080439895 | HEATR2 | ADRBK1 |
| HEATR2 | FLNA | 0.081322228 | HEATR2 | FLNA |
| HEATR2 | GFPT1 | 0.094196065 | HEATR2 | GFPT1 |
| ARMC1 | HEATR2 | 0.070321292 | ARMC1 | HEATR2 |
| CSTF1 | HEATR2 | 0.077196093 | CSTF1 | HEATR2 |