Metazoan complexes |
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Details of MED17 gene in Homo sapiens
IDs | |||||||||
---|---|---|---|---|---|---|---|---|---|
Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
| MED17 | ARC77,CRSP6,DRIP77,DRIP80,TRAP80 | Q9NVC6 | MED17_HUMAN | 9440 | ENSG00000042429 | Mediator of RNA polymerase II transcription subunit 17 | SPROT |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | OMIM id | ||||||||
Microcephaly, postnatal progressive, with seizures and brain atrophy (MCPHSBA) [MIM:613668]: A disorder characterized by postnatal progressive microcephaly and severe developmental retardation associated with cerebral and cerebellar atrophy. Infants manifest swallowing difficulties leading to failure to thrive, jitteriness, poor visual fixation, truncal arching, seizures. There is no acquisition of developmental milestones and patients suffer from marked spasticity and profound retardation. Progressive microcephaly becomes evident few months after birth. Note=The disease is caused by mutations affecting the gene represented in this entry. | 613668 |
Orthologs in other species | |||||||||
---|---|---|---|---|---|---|---|---|---|
M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
Med17 | MED17 | mdt-17 | Sp-Med17... |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
---|---|---|---|---|---|---|---|---|---|
MED17 | MED12 | 0.235741856 | MED17 | MED12 | cpx11 | yes | yes | yes | Known |
MED17 | MED13 | 1 | MED17 | MED13 | cpx11 | yes | yes | no | Known |
MED17 | MED16 | 1 | MED17 | MED16 | cpx11 | yes | yes | no | Known |
MED20 | MED17 | 1 | MED20 | MED17 | cpx11 | yes | yes | yes | Known |
MED19 | MED17 | 1 | MED19 | MED17 | cpx11 | yes | yes | yes | Known |
MED27 | MED17 | 1 | MED27 | MED17 | cpx11 | yes | yes | no | Known |
MED18 | MED17 | 1 | MED18 | MED17 | cpx11 | yes | yes | yes | Known |
MED24 | MED17 | 1 | MED24 | MED17 | cpx11 | yes | yes | no | Known |
MED15 | MED17 | 0.684946766 | MED15 | MED17 | cpx11 | yes | yes | no | Known |
MED6 | MED17 | 1 | MED6 | MED17 | cpx11 | yes | yes | no | Known |
MED14 | MED17 | 1 | MED14 | MED17 | cpx11 | yes | yes | no | Known |
MED11 | MED17 | 0.996202742 | MED11 | MED17 | cpx716 | yes | yes | yes | Known |
MED1 | MED17 | 1 | MED1 | MED17 | cpx11 | yes | yes | yes | Known |
MED8 | MED17 | 1 | MED8 | MED17 | cpx11 | yes | yes | no | Known |
MED29 | MED17 | 1 | MED29 | MED17 | cpx11 | yes | yes | no | Known |
MED4 | MED17 | 1 | MED4 | MED17 | cpx11 | yes | yes | no | Known |