Metazoan complexes |
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Emili & Marcotte labs |
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Details of OGDH gene in Homo sapiens
IDs | |||||||||
---|---|---|---|---|---|---|---|---|---|
Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
| OGDH | --- | Q02218 | ODO1_HUMAN | 4967 | ENSG00000105953 | 2-oxoglutarate dehydrogenase, mitochondrial | SPROT |
Phenotypes
Abnormality of acid-base homeostasis, Abnormality of metabolism/homeostasis, Abnormality of muscle physiology, Abnormality of the musculature, Abnormal muscle tone, Acidosis, All, Autosomal recessive inheritance, Congenital lactic acidosis, Increased serum lactate, Lactic acidosis, Metabolic acidosis, Mode of inheritance, Muscular hypotonia, Phenotypic abnormality.
Orthologs in other species | |||||||||
---|---|---|---|---|---|---|---|---|---|
M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
Ogdh | Nc73EF | T22B11.5 | SPU_014372 |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
---|---|---|---|---|---|---|---|---|---|
DLD | OGDH | 1 | DLD | OGDH | cpx165 | no | yes | yes | Known |
OGDH | DLST | 1 | OGDH | DLST | cpx165 | no | yes | yes | Known |
OGDH | DLAT | 1 | OGDH | DLAT | cpx165 | no | no | no | Novel |
OGDH | PDHA1 | 0.074401929 | OGDH | PDHA1 | cpx165 | no | yes | no | Known |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
---|---|---|---|---|
OGDH | COX5A | 0.101857878 | OGDH | COX5A |
ATP1B3 | OGDH | 0.08888211 | ATP1B3 | OGDH |
NDUFS2 | OGDH | 0.114903207 | NDUFS2 | OGDH |
OGDH | CYC1 | 0.089937501 | OGDH | CYC1 |
OGDH | ATP5H | 0.164540995 | OGDH | ATP5H |
OGDH | NDUFS4 | 0.07624609 | OGDH | NDUFS4 |
SUCLG1 | OGDH | 0.164690585 | SUCLG1 | OGDH |
OGDH | SUCLG2 | 0.202669526 | OGDH | SUCLG2 |