|
Metazoan complexes |
Emili & Marcotte labs |
Please wait while page loads....
- Home
-
H.sapiens
-
M.musculus
-
D.melanogaster
-
C.elegans
-
S.purpuratus
-
Conserved map
-
PPI Projections
- Download
- Help
- Contact
Details of POLR3A gene in Homo sapiens
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
|
| POLR3A | --- | O14802 | RPC1_HUMAN | 11128 | ENSG00000148606 | DNA-directed RNA polymerase III subunit RPC1 | SPROT | |
Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | OMIM id | ||||||||
| Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism (HLD7) [MIM:607694]: An autosomal recessive neurodegenerative disorder characterized by childhood onset of progressive motor decline manifest as spasticity, ataxia, tremor, and cerebellar signs, as well as mild cognitive regression. Other features may include hypodontia or oligodontia and hypogonadotropic hypogonadism. There is considerable inter- and intrafamilial variability. Note=The disease is caused by mutations affecting the gene represented in this entry. | 607694 | ||||||||
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
| Polr3a | CG17209 | rpc-1 | --- | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| POLR3A | POLR1B | 0.916696785 | POLR3A | POLR1B | cpx976 | no | no | no | Novel |
| POLR3A | POLR2E | 0.990358654 | POLR3A | POLR2E | cpx732 | no | yes | yes | Known |
| POLR3A | POLR2H | 0.973600099 | POLR3A | POLR2H | cpx976 | no | yes | yes | Known |
| POLR3A | POLR1C | 0.901551078 | POLR3A | POLR1C | cpx780 | no | yes | yes | Known |
| POLR3A | POLR1D | 0.923140506 | POLR3A | POLR1D | cpx771 | no | yes | yes | Known |
| POLR3A | POLR2A | 0.97262391 | POLR3A | POLR2A | cpx976 | no | no | no | Novel |
| POLR3A | POLR3K | 0.820588123 | POLR3A | POLR3K | cpx36 | no | yes | yes | Known |
| POLR3A | POLR3B | 1 | POLR3A | POLR3B | cpx36 | no | yes | yes | Known |
| POLR3A | POLR3C | 1 | POLR3A | POLR3C | cpx36 | no | yes | yes | Known |
| POLR3A | POLR3D | 1 | POLR3A | POLR3D | cpx36 | no | yes | yes | Known |
| POLR3A | POLR3E | 1 | POLR3A | POLR3E | cpx36 | no | yes | yes | Known |
| POLR3A | POLR3F | 1 | POLR3A | POLR3F | cpx36 | no | yes | yes | Known |
| POLR3A | POLR3G | 1 | POLR3A | POLR3G | cpx36 | no | no | no | Novel |
| POLR3A | POLR3H | 1 | POLR3A | POLR3H | cpx36 | no | yes | yes | Known |
| POLR3A | CRCP | 1 | POLR3A | CRCP | cpx36 | no | yes | yes | Known |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
|---|---|---|---|---|
| POLR3A | HDAC2 | 0.108656537 | POLR3A | HDAC2 |
| POLR1A | POLR3A | 0.749097668 | POLR1A | POLR3A |
| POLR3A | MRPL22 | 0.376517736 | POLR3A | MRPL22 |
| POLR3A | GTF3C3 | 0.080022099 | POLR3A | GTF3C3 |
| POLR3A | TSR1 | 0.085519401 | POLR3A | TSR1 |
| POLR3A | RPS5 | 0.226281931 | POLR3A | RPS5 |
| MRPL11 | POLR3A | 0.300574591 | MRPL11 | POLR3A |
| POLR3A | MRPL17 | 0.23962606 | POLR3A | MRPL17 |
| SMARCA5 | POLR3A | 0.283165855 | SMARCA5 | POLR3A |
| POLR3A | MRPS7 | 0.076390829 | POLR3A | MRPS7 |
| POLR3A | SMARCA4 | 0.089715156 | POLR3A | SMARCA4 |
| POLR3A | MRPL54 | 0.074571853 | POLR3A | MRPL54 |
| POLR3A | MRPL24 | 0.136765146 | POLR3A | MRPL24 |
| POLR3A | HDAC1 | 0.076219667 | POLR3A | HDAC1 |
| POLR2B | POLR3A | 0.558777452 | POLR2B | POLR3A |
| POLR3A | TUFM | 0.18944591 | POLR3A | TUFM |
| POLR3A | IPO9 | 0.121551531 | POLR3A | IPO9 |
| MRPL2 | POLR3A | 0.23106722 | MRPL2 | POLR3A |