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Metazoan complexes |
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Details of SS18 gene in Homo sapiens
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | ENSEMBL ID | Description | Source | |
|
| SS18 | SSXT,SYT | Q15532 | SSXT_HUMAN | 6760 | ENSG00000141380 | Protein SSXT | SPROT | |
Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | OMIM id | ||||||||
| Note=A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X18)(p11.2q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). | --- | ||||||||
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M. musculus | D. melonogaster | C. elegans | S. purpuratus | ||||||
| Ss18 | CG10555 | ZK973.9 | Sp-Ss18L | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| SS18 | ARID1A | 1 | SS18 | ARID1A | cpx6 | no | no | no | Novel |
| SS18 | ARID1B | 1 | SS18 | ARID1B | cpx6 | no | no | no | Novel |
| SS18 | DPF2 | 1 | SS18 | DPF2 | cpx6 | no | no | no | Novel |
| SMARCB1 | SS18 | 1 | SMARCB1 | SS18 | cpx6 | no | yes | yes | Known |
| SMARCA4 | SS18 | 1 | SMARCA4 | SS18 | cpx6 | no | no | no | Novel |
| SMARCC2 | SS18 | 1 | SMARCC2 | SS18 | cpx6 | no | no | no | Novel |
| SMARCD1 | SS18 | 1 | SMARCD1 | SS18 | cpx6 | no | yes | no | Known |
| SMARCD2 | SS18 | 1 | SMARCD2 | SS18 | cpx6 | no | no | no | Novel |
| SMARCE1 | SS18 | 1 | SMARCE1 | SS18 | cpx6 | no | no | no | Novel |
| BCL7C | SS18 | 1 | BCL7C | SS18 | cpx6 | no | no | no | Novel |
| SMARCC1 | SS18 | 1 | SMARCC1 | SS18 | cpx6 | no | no | no | Novel |
| SMARCA2 | SS18 | 1 | SMARCA2 | SS18 | cpx6 | no | yes | yes | Known |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
H. sapiens gene 1 |
H. sapiens gene 2 |
|---|---|---|---|---|