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Details of SS18 gene in Homo sapiens
Disease |
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| Disease |
OMIM id |
| Note=A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X18)(p11.2q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). |
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Orthologs in other species |
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| M. musculus |
D. melonogaster |
C. elegans |
S. purpuratus |
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