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Details of hda-1 gene in Caenorhabditis elegans
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
|
| hda-1 | --- | O17695 | HDA1_CAEEL | 179959 | WBGene00001834 | C53A5.3 | Histone deacetylase 1 | SPROT |
Phenotypes
apoptosis increased, cell polarity variant, chromosome segregation variant karyomeres early emb, ectopic expression transgene, embryonic arrest, embryonic lethal, epithelial development variant, extra gonad arms, gonad development variant, intestinal development variant, larval arrest, maternal sterile, mRNA levels increased, multivulva, organism development variant, organism UV hypersensitive, pattern of transgene expression variant, peptide uptake by intestinal cell decreased, pharyngeal morphology variant, pharynx unattached, protein acetylation variant, protein methylation variant, protein subcellular localization variant, protruding vulva, rays displaced, rays missing, receptor mediated endocytosis defective, reduced brood size, somatic gonad development variant, spontaneous mutation rate increased, sterile progeny, tail morphology variant, transgene expression increased, ventral closure defective, vulva cell fate specification variant, vulval cell induction variant.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
| HDAC1 | Hdac1 | Rpd3 | HDAC1... | HDAC2 | Hdac2 | Rpd3 | HDAC1... | ||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| CHD5 | HDAC1 | 0.281955848 | chd-3:let-418 | hda-1 | cpx52 | no | yes | no | Known |
| CHD4 | HDAC1 | 0.519960147 | chd-3:let-418 | hda-1 | cpx52 | yes | yes | yes | Known |
| CHD4 | HDAC2 | 0.517435647 | chd-3:let-418 | hda-1 | cpx52; cpx977 | yes | yes | yes | Known |
| HDAC1 | HDAC2 | 1 | hda-1 | hda-1 | cpx52; cpx321 | yes | yes | yes | Known |
| CHD5 | HDAC2 | 0.271787587 | chd-3:let-418 | hda-1 | cpx52 | no | yes | no | Known |
| MORF4L1 | HDAC2 | 0.64303215 | mrg-1 | hda-1 | cpx52 | no | yes | yes | Known |
| RBBP4 | HDAC2 | 0.838847562 | lin-53 | hda-1 | cpx977 | yes | yes | yes | Known |
| HDAC1 | MORF4L1 | 0.653964515 | hda-1 | mrg-1 | cpx52 | no | yes | yes | Known |
| HDAC1 | MTA1 | 0.971591193 | hda-1 | lin-40 | cpx52 | yes | yes | yes | Known |
| HDAC2 | MTA1 | 0.885658265 | hda-1 | lin-40 | cpx52 | yes | yes | yes | Known |
| HDAC2 | MTA2 | 0.943058148 | hda-1 | lin-40 | cpx977 | yes | yes | yes | Known |
| HDAC1 | TLE3 | 0.681550064 | hda-1 | unc-37 | cpx52 | yes | yes | yes | Known |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
|---|---|---|---|---|
| POLR3A | HDAC2 | 0.108656537 | rpc-1 | hda-1 |
| MORF4L2 | HDAC2 | 0.354076878 | mrg-1 | hda-1 |
| HDAC1 | MTA2 | 0.88843655 | hda-1 | lin-40 |
| HDAC2 | MTA3 | 0.853647492 | hda-1 | lin-40 |
| HDAC1 | MTA3 | 0.892433435 | hda-1 | lin-40 |
| HDAC2 | CRCP | 0.071423647 | hda-1 | M106.7 |
| POLR3A | HDAC1 | 0.076219667 | rpc-1 | hda-1 |
| MAPK14 | HDAC1 | 0.108312487 | pmk-1 | hda-1 |
| MAPK11 | HDAC1 | 0.106890298 | pmk-1 | hda-1 |