Metazoan complexes |
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Details of paa-1 gene in Caenorhabditis elegans
IDs | |||||||||
---|---|---|---|---|---|---|---|---|---|
Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
| paa-1 | --- | Q09543 | 2AAA_CAEEL | 175750 | WBGene00003901 | F48E8.5 | Probable serine/threonine-protein phosphatase PP2A regulatory subunit | SPROT |
Phenotypes
accumulated germline cell corpses, apoptosis increased, apoptosis variant, cell cycle delayed, cell division variant, cell membrane organization biogenesis variant, cell secretion variant, centriole biogenesis variant, centrosome biogenesis variant, chromosome alignment variant, chromosome condensation variant, chromosome decondensation failure, complex phenotype early emb, diplotene absent during oogenesis, diplotene region organization variant, embryonic lethal, exploded through vulva, germ cell compartment anucleate, germ cell compartment expansion variant, germ cell compartment large, germ cell compartment morphology variant, germ cell compartment multinucleate, germ cell compartment size variant, germ cell compartment small, germ cell morphology variant, germline nuclear positioning variant, gonad migration variant, gonad morphology variant, gonad vesiculated, interphase entry defective early emb, larval lethal, level of protein expression variant, locomotion variant, maternal sterile, mitosis variant, mitotic spindle defective early emb, multiple nuclei oocyte, nuclear appearance variant, nuclear envelope assembly variant early emb, nuclei small, oocyte morphology variant, oocytes lack nucleus, oocytes small, organism development variant, pachytene progression during oogenesis variant, pachytene region organization variant, pattern of transgene expression variant, protein expression reduced, RAB-11 recycling endosome localization variant, RAB-11 recycling endosome morphology variant, rachis morphology variant, rachis narrow, receptor mediated endocytosis defective, reduced brood size, RNAi resistant, sick, somatic transgene silencing variant, spindle position orientation defective early emb, sterile, transgene expression increased, transgene subcellular localization variant.
Orthologs in other species | |||||||||
---|---|---|---|---|---|---|---|---|---|
H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
PPP2R1A | Ppp2r1a | Pp2A-29B | Sp-Pr65a | PPP2R1B | Ppp2r1b | Pp2A-29B | Sp-Pr65a |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
---|---|---|---|---|---|---|---|---|---|
PPP2R1A | PPP2R5A | 0.999998123 | paa-1 | pptr-1 | cpx24 | no | yes | yes | Known |
PPP2R1A | PPP2R5E | 0.999999372 | paa-1 | pptr-1 | cpx24 | no | yes | yes | Known |
PPP2R1B | PPP2R5E | 0.999999918 | paa-1 | pptr-1 | cpx24 | no | yes | yes | Known |
PPP2R2A | PPP2R1A | 0.424266213 | sur-6 | paa-1 | cpx24 | yes | yes | yes | Known |
AHSA1 | PPP2R1A | 0.035231976 | C01G10.8 | paa-1 | cpx206 | no | yes | no | Known |
SLC25A3 | PPP2R1A | 0.554650537 | F01G4.6 | paa-1 | cpx35; cpx105 | no | yes | no | Known |
PPP2CB | PPP2R1A | 0.685174055 | let-92 | paa-1 | cpx24 | yes | yes | yes | Known |
PPP2R2B | PPP2R1A | 0.281992849 | sur-6 | paa-1 | cpx24 | no | yes | yes | Known |
CLTC | PPP2R1A | 0.182702163 | chc-1 | paa-1 | cpx35 | no | yes | no | Known |
PPP2R2D | PPP2R1A | 0.190064627 | sur-6 | paa-1 | cpx24 | no | yes | yes | Known |
PPP2CA | PPP2R1A | 0.762202551 | let-92 | paa-1 | cpx24 | yes | yes | yes | Known |
PPP2R1A | PPP2R1B | 1 | paa-1 | paa-1 | cpx24 | yes | no | no | Known |
CLTC | PPP2R1B | 0.372744096 | chc-1 | paa-1 | cpx796 | no | yes | no | Known |
PPP2CB | PPP2R1B | 0.932278698 | let-92 | paa-1 | cpx24 | no | yes | yes | Known |
PPP2CA | PPP2R1B | 0.903756248 | let-92 | paa-1 | cpx24 | yes | yes | yes | Known |
PPP2R2A | PPP2R1B | 0.556901069 | sur-6 | paa-1 | cpx24 | no | yes | yes | Known |
PPP2R1A | ACADM | 0.246102015 | paa-1 paa-1 | acdh-10 acdh-7 | cpx35; cpx206 | no | yes | no | Known |
PPP2R1A | CANX | 0.323407645 | paa-1 | cnx-1 | cpx35; cpx23; cpx105 | no | yes | no | Known |
PPP2R1A | HSP90B1 | 0.04293672 | paa-1 | enpl-1 | cpx23 | no | yes | no | Known |
PPP2R1A | IDH3A | 0.342299437 | paa-1 | F43G9.1 | cpx35; cpx105; cpx23 | no | yes | no | Known |
PPP2R1A | UQCRC2 | 0.850230296 | paa-1 paa-1 paa-1 | ucr-2.1 ucr-2.2 ucr-2.3 | cpx23; cpx35 | no | yes | no | Known |
PPP2R1A | RPN1 | 0.36828532 | paa-1 | ribo-1 | cpx23 | no | yes | no | Known |
PPP2R1A | EPRS | 0.055677681 | paa-1 | ears-1 | cpx23 | no | yes | no | Known |
PPP2R1A | CCT3 | 0.053774492 | paa-1 | cct-3 | cpx35 | no | yes | no | Known |
Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
---|---|---|---|---|
PPP2R1A | TMCO1 | 0.076767228 | paa-1 | F22B5.10 |
PPP2R1A | NFS1 | 0.210974705 | paa-1 | B0205.6 |
PPP2R1A | SCD | 0.108267246 | paa-1 | fat-6 |
PPP2R1A | PC | 0.072140255 | paa-1 | pyc-1 |
CYC1 | PPP2R1A | 0.091037203 | cyc-1 | paa-1 |
SLC25A3 | PPP2R1B | 0.482741524 | F01G4.6 | paa-1 |
PPP2R1A | ATP1A1 | 0.083791086 | paa-1 | eat-6 |
VPS13D | PPP2R1A | 0.081533204 | C25H3.8 | paa-1 |
CLTCL1 | PPP2R1A | 0.18773247 | chc-1 | paa-1 |
PPP2R1B | RPN1 | 0.384314808 | paa-1 | ribo-1 |
PPP2R1A | SCD5 | 0.080993148 | paa-1 | fat-6 |
PPP2R1A | TOMM22 | 0.136349881 | paa-1 | tomm-22 |
PPP2R1A | EHD1 | 0.071013302 | paa-1 | rme-1 |
ACADM | PPP2R1B | 0.271963324 | acdh-7, acdh-10, acdh-8 | paa-1 |
PPP2R1A | HSD17B12 | 0.190427409 | paa-1 | let-767, stdh-3, stdh-4 |
PPP2R1A | ATAD3B | 0.078361674 | paa-1 | atad-3 |