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Metazoan complexes |
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Details of pdha-1 gene in Caenorhabditis elegans
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
|
| pdha-1 | --- | P52899 | --- | 3565996 | --- | T05H10.6 | Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:UniProtKB/Swiss-Prot Acc:P52899] | ENSEMBL |
Phenotypes
cell membrane organization biogenesis variant, clear, embryonic lethal, general pace of development defective early emb, germ cell compartment morphology variant, gonad migration variant, life span variant, oocyte number decreased, oogenesis variant, pattern of transgene expression variant, receptor mediated endocytosis defective, reduced brood size, shortened life span, slow growth.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
| PDHA2 | --- | l(1)G0334 | Sp-Pdha1 | PDHA1 | Pdha1 | l(1)G0334 | Sp-Pdha1 | ||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| PDHA1 | DLAT | 0.795159522 | pdha-1 | F23B12.5 | cpx165; cpx292 | no | yes | yes | Known |
| PDHB | PDHA2 | 0.99998759 | C04C3.3 | pdha-1 | cpx292 | no | yes | yes | Known |
| PDHB | PDHA1 | 1 | C04C3.3 | pdha-1 | cpx292 | no | yes | yes | Known |
| DLD | PDHA1 | 0.288901945 | dld-1 | pdha-1 | cpx165 | no | no | no | Novel |
| OGDH | PDHA1 | 0.074401929 | T22B11.5 | pdha-1 | cpx165 | no | yes | no | Known |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
|---|---|---|---|---|
| HNRNPL | PDHA1 | 0.072174588 | C44B7.2 | pdha-1 |
| PDHA1 | RAB7A | 0.099546295 | pdha-1 | rab-7 |
| LDHA | PDHA1 | 0.138860387 | ldh-1 | pdha-1 |
| ANXA11 | PDHA1 | 0.10505737 | nex-2 | pdha-1 |
| TRIM3 | PDHA1 | 0.089506096 | nhl-1 | pdha-1 |
| SDHB | PDHA2 | 0.070654294 | sdhb-1 | pdha-1 |
| NDUFV1 | PDHA1 | 0.167976563 | nuo-1 | pdha-1 |
| LDHB | PDHA1 | 0.128580935 | ldh-1 | pdha-1 |
| SDHB | PDHA1 | 0.235499068 | sdhb-1 | pdha-1 |
| TOMM22 | PDHA1 | 0.083371893 | tomm-22 | pdha-1 |
| TRIM2 | PDHA1 | 0.076304015 | nhl-1 | pdha-1 |
| PDHA1 | ATP1B1 | 0.0951365 | pdha-1 | nkb-3, nkb-1 |