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Details of rab-5 gene in Caenorhabditis elegans
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
|
| rab-5 | --- | I7FXD3 | --- | 172755 | --- | F26H9.6 | Protein RAB-5 [Source:RefSeq peptide Acc:NP_492481] | ENSEMBL |
Phenotypes
accumulated germline cell corpses, accumulated somatic cell corpses, aldicarb resistant, apoptosis increased, apoptosis variant, cell death variant, complex phenotype early emb, copper response variant, cytokinesis variant emb, cytoplasmic appearance defective early emb, diplotene region organization variant, embryonic lethal, endocytic transport defect, endocytic transport variant, engulfment variant, fat content reduced, germ cell compartment expansion variant, germ cell compartment morphology variant, germ cell compartment multinucleate, germ cell morphology variant, germline nuclear positioning variant, gonad morphology variant, larval arrest, larval lethal, lethal, lipid metabolism variant, lysosome-related organelle morphology variant, membrane trafficking variant, molt defect, multiple nuclei early emb, oocyte number decreased, pathogen induced death increased, pathogen susceptibility increased, pattern of transgene expression variant, population fitness variant, protein aggregation variant, protein degradation variant, protein secretion variant, RAB-11 recycling endosome morphology variant, rachis narrow, receptor mediated endocytosis defective, reduced brood size, shortened life span, sterile, transgene expression increased, transgene subcellular localization variant.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
| RAB5A | Rab5a | Rab5 | Sp-Rab5l | RAB5B | Rab5b | Rab5 | Sp-Rab5l | RAB5C | Rab5c | Rab5 | Sp-Rab5l |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| RAB5C | RAB8B | 0.442382914 | rab-5 | rab-8 | cpx8 | no | no | no | Novel |
| RAB5B | UQCRC2 | 0.828139707 | rab-5 rab-5 | ucr-2.1 ucr-2.2 | cpx161 | no | yes | no | Known |
| RAB5B | RAB1A | 0.716111665 | rab-5 | rab-1 | cpx8 | no | yes | no | Known |
| RAB5A | RAB1A | 0.576929681 | rab-5 | rab-1 | cpx8 | no | yes | no | Known |
| RAB5C | RAB1A | 0.698096712 | rab-5 | rab-1 | cpx8 | no | yes | no | Known |
| RAB5B | RAB1B | 0.46151178 | rab-5 | rab-1 | cpx8 | no | yes | no | Known |
| RAB5C | RAB1B | 0.487420889 | rab-5 | rab-1 | cpx8 | no | yes | no | Known |
| RAB5A | RAB1B | 0.59255942 | rab-5 | rab-1 | cpx8 | no | yes | no | Known |
| RAB5A | RAB2A | 0.072726612 | rab-5 | unc-108 | cpx8 | no | yes | no | Known |
| RAB5C | RAB2A | 0.072243471 | rab-5 | unc-108 | cpx8 | no | yes | no | Known |
| RAB5B | RAB2A | 0.111073001 | rab-5 | unc-108 | cpx8 | no | yes | no | Known |
| RAP1A | RAB5A | 0.133391217 | rap-1 | rab-5 | cpx8 | no | yes | no | Known |
| RAB11A | RAB5A | 0.351367362 | rab-11.1 | rab-5 | cpx8 | no | yes | no | Known |
| CDC42 | RAB5A | 0.030269705 | cdc-42 | rab-5 | cpx8 | no | yes | no | Known |
| RAP1B | RAB5B | 0.237876812 | rap-1 | rab-5 | cpx161 | no | yes | no | Known |
| RAB11A | RAB5B | 0.261321986 | rab-11.1 | rab-5 | cpx8 | no | no | no | Novel |
| RAP1A | RAB5B | 0.148419014 | rap-1 | rab-5 | cpx8; cpx161 | no | yes | no | Known |
| RAB11B | RAB5B | 0.485899804 | rab-11.1 | rab-5 | cpx8 | no | no | no | Novel |
| CDC42 | RAB5B | 0.041970174 | cdc-42 | rab-5 | cpx161; cpx8 | no | no | no | Novel |
| RAB11B | RAB5C | 0.493044624 | rab-11.1 | rab-5 | cpx8 | no | no | no | Novel |
| RAB11A | RAB5C | 0.284603124 | rab-11.1 | rab-5 | cpx8 | no | no | no | Novel |
| RAP1A | RAB5C | 0.137891352 | rap-1 | rab-5 | cpx8 | no | yes | no | Known |
| RAB5A | RAB8A | 0.455445624 | rab-5 | rab-8 | cpx8 | no | no | no | Novel |
| RAB5B | RAB8A | 0.533900923 | rab-5 | rab-8 | cpx8 | no | no | no | Novel |
| RAB5C | RAB8A | 0.655615757 | rab-5 | rab-8 | cpx8 | no | no | no | Novel |
| RAB5A | RAB8B | 0.583006864 | rab-5 | rab-8 | cpx8 | no | no | no | Novel |
| RAB5A | RAB11B | 0.541626453 | rab-5 | rab-11.1 | cpx8 | no | no | no | Novel |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
|---|---|---|---|---|
| RAB5B | ETFA | 0.773049938 | rab-5 | F27D4.1 |
| RAB5C | ETFA | 0.626498837 | rab-5 | F27D4.1 |
| RAP1B | RAB5A | 0.103633027 | rap-1 | rab-5 |
| ARF5 | RAB5B | 0.076454214 | arf-3 | rab-5 |
| RAB5B | ARF1 | 0.627099893 | rab-5 | arf-1.2 |
| LDHB | RAB5A | 0.463338022 | ldh-1 | rab-5 |
| RAB5C | LDHA | 0.372117133 | rab-5 | ldh-1 |
| RAB5B | TUFM | 0.08223903 | rab-5 | tufm-1 |
| RAB5C | LDHAL6A | 0.257798184 | rab-5 | ldh-1 |
| LGALS1 | RAB5C | 0.074462414 | lec-6 | rab-5 |
| RAB5B | CTSD | 0.111213283 | rab-5 | asp-4 |
| RAB5C | UQCRC2 | 0.898778151 | rab-5 | ucr-2.2, ucr-2.3, ucr-2.1 |
| RAB5C | LDHB | 0.417400515 | rab-5 | ldh-1 |
| RAB5C | PSMC2 | 0.136891912 | rab-5 | rpt-1 |
| RAB5C | ARF1 | 0.262142003 | rab-5 | arf-1.2 |
| RAB5C | ARL8A | 0.091227022 | rab-5 | arl-8 |
| RAB5C | LDHAL6B | 0.534104215 | rab-5 | ldh-1 |
| ARF1 | RAB5A | 0.453041323 | arf-1.2 | rab-5 |
| LDHA | RAB5A | 0.552183287 | ldh-1 | rab-5 |
| RAB5B | CLTC | 0.078379198 | rab-5 | chc-1 |
| RAP1B | RAB5C | 0.112853794 | rap-1 | rab-5 |
| CTSD | RAB5A | 0.079637644 | asp-4 | rab-5 |
| RAB5A | UQCRC2 | 0.804666175 | rab-5 | ucr-2.2, ucr-2.3, ucr-2.1 |