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Details of ran-1 gene in Caenorhabditis elegans
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
|
| ran-1 | --- | O17915 | RAN_CAEEL | 176503 | WBGene00004302 | K01G5.4 | GTP-binding nuclear protein ran-1 | SPROT |
Phenotypes
accumulated germline cell corpses, apoptosis increased, cell cell contacts variant four emb, cell cycle slow early emb, cell division slow, cell membrane organization biogenesis variant, chromosome condensation variant, chromosome morphology variant, cytokinesis fails early emb, diplotene absent during oogenesis, diplotene region organization variant, embryonic lethal, embryo osmotic pressure sensitive early emb, endoplasmic reticulum morphology variant, germ cell compartment anucleate, germ cell compartment expansion absent, germ cell compartment expansion variant, germ cell compartment morphology variant, germ cell compartment size variant, germ cell compartment small, gonad morphology variant, gonad vesiculated, inhibition of oocyte maturation variant, larval arrest, larval lethal, lethal, locomotion variant, lysosome-related organelle morphology variant, maternal pronucleus indistinct early emb, maternal sterile, microtubule organization biogenesis variant, microtubule polymerization variant, mitotic spindle defective early emb, multiple nuclei oocyte, no oocytes, nuclear envelope assembly variant early emb, nuclear envelope breakdown variant, nuclei enlarged, nuclei small, oocyte morphology variant, oocyte number decreased, oocytes lack nucleus, oocytes small, P0 spindle position defective early emb, pachytene region organization variant, pattern protein expression variant, pronuclear nuclear appearance defective early emb, pronuclear size defective early emb, pronucleus centrosomes defective early emb, protein aggregation variant, protein subcellular localization variant, RAB-11 recycling endosome localization variant, RAB-11 recycling endosome morphology variant, rachis morphology variant, rachis narrow, reduced brood size, sick, spindle defective early emb, sterile, transgene expression reduced, transgene subcellular localization variant.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
| RAN | Ran | ran | Sp-Ran | ||||||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| RAN | POR | 0.037019894 | ran-1 | emb-8 | cpx144; cpx147 | no | no | no | Novel |
| RAN | PSMD12 | 0.068739241 | ran-1 | rpn-5 | cpx967 | no | no | no | Novel |
| RCC1 | RAN | 0.824923366 | ran-3 | ran-1 | cpx147; cpx41; cpx144 | no | yes | yes | Known |
| CSE1L | RAN | 0.197296712 | xpo-2 | ran-1 | cpx41 | no | yes | yes | Known |
| IPO5 | RAN | 0.407413961 | imb-3 | ran-1 | cpx967 | no | yes | yes | Known |
| TNPO1 | RAN | 0.413974883 | imb-2 | ran-1 | cpx41 | no | yes | yes | Known |
| EIF3I | RAN | 0.086153908 | eif-3.I | ran-1 | cpx967 | no | no | no | Novel |
| KPNB1 | RAN | 0.545863528 | imb-1 | ran-1 | cpx967 | yes | yes | yes | Known |
| RAN | RANBP6 | 0.231012082 | ran-1 | imb-3 | cpx41 | no | yes | yes | Known |
| RAN | XPO1 | 0.313354713 | ran-1 | xpo-1 | cpx144; cpx147 | yes | yes | yes | Known |