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Metazoan complexes |
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Details of ric-4 gene in Caenorhabditis elegans
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
|
| ric-4 | --- | O62414 | --- | --- | WBGene00004364 | Y22F5A.3 | ric-4 encodes an ortholog of vertebrate SNAP-25 and S. cerevisiae Sec9p SNAP-25 is associated with synaptosomes, required for axonal growth in vivo, and targeted by botulinum neurotoxins UNC-86 and MEC-3 are required for ric-4 expression, and act on a regulatory element (I2h) in ric-4 conserved between the first introns of C. elegans and C. briggsae ric-4 genes other conserved motifs in the promoter region (P1 and P2) and first intron (I1h, I1m, I2h, and I2m) are required for ric-4 expression in DA and DD motor neurons (P1), DB and DA neurons (I1m and I2m), amphid and phasmid neurons (P2), pharyngeal neurons (I1h), and mechanosensory neurons (I2h) loss of ric-4 function via RNAi results in aldicarb resistance, indicating that ric-4 plays a role in synapse structure and function. | WORMBASE |
| ric-4 | --- | A5PEW5 | --- | --- | WBGene00004364 | Y22F5A.3 | ric-4 encodes an ortholog of vertebrate SNAP-25 and S. cerevisiae Sec9p SNAP-25 is associated with synaptosomes, required for axonal growth in vivo, and targeted by botulinum neurotoxins UNC-86 and MEC-3 are required for ric-4 expression, and act on a regulatory element (I2h) in ric-4 conserved between the first introns of C. elegans and C. briggsae ric-4 genes other conserved motifs in the promoter region (P1 and P2) and first intron (I1h, I1m, I2h, and I2m) are required for ric-4 expression in DA and DD motor neurons (P1), DB and DA neurons (I1m and I2m), amphid and phasmid neurons (P2), pharyngeal neurons (I1h), and mechanosensory neurons (I2h) loss of ric-4 function via RNAi results in aldicarb resistance, indicating that ric-4 plays a role in synapse structure and function. | WORMBASE |
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
| SNAP23 | Snap23 | --- | --- | SNAP25 | Snap25 | Snap24... | SPU_006859 | ||
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
|---|---|---|---|---|