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Details of unc-116 gene in Caenorhabditis elegans
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
|
| unc-116 | khc-1 | P34540 | KINH_CAEEL | 176179 | WBGene00006840 | R05D3.7 | Kinesin heavy chain | SPROT |
Phenotypes
axon fasciculation variant, axon guidance variant, body wall muscle sarcomere morphology variant, coiler, cord commissures fail to reach target, dendrite development variant, dumpy, early endosome localization variant, egg laying defective, embryonic development variant, embryonic lethal, exploded through vulva, germ cell morphology variant, growth rate variant, late endosome localization variant, locomotion variant, maternal sterile, meiotic chromosome segregation variant, meiotic spindle assembly defective, meiotic spindle defective, meiotic spindle positioning defective, meiotic spindle rotation defective, microtubule organization biogenesis variant, mitochondria morphology variant muscle, muscle arm development defective, myopodia present, organism morphology variant, polar body number defective early emb, postembryonic development variant, protein degradation variant, protein expression reduced, protruding vulva, RAB-11 recycling endosome localization variant, RAB-11 recycling endosome morphology variant, reduced brood size, roller, slow growth, sterile, transgene expression reduced, transgene subcellular localization variant, Variant.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
| KIF5A | Kif5a | Khc | Sp-Khc | KIF5C | Kif5c | Khc | Sp-Khc | KIF5B | Kif5b | Khc | Sp-Khc |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| KLC4 | KIF5A | 1 | klc-2 | unc-116 | cpx488 | no | yes | no | Known |
| KIF5A | 1 | klc-2 | unc-116 | cpx690 | no | yes | yes | Known | |
| KLC2 | KIF5C | 1 | klc-2 | unc-116 | cpx692 | no | yes | no | Known |
| KLC4 | KIF5C | 1 | klc-2 | unc-116 | cpx692 | no | yes | no | Known |
| KIF5C | 1 | klc-2 | unc-116 | cpx691 | no | yes | no | Known | |
| KLC2 | KIF5B | 1 | klc-2 | unc-116 | cpx489 | no | yes | yes | Known |
| KLC4 | KIF5B | 1 | klc-2 | unc-116 | cpx686 | no | yes | no | Known |
| KIF5B | 1 | klc-2 | unc-116 | cpx690 | no | yes | yes | Known | |