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Details of ARHGAP26 gene in Homo sapiens
IDs |
Link outs |
Gene Name |
Alias |
Uniprot ID |
SwissProt ID |
NCBI gene ID |
ENSEMBL ID |
Description |
Source |
| ARHGAP26 | GRAF,KIAA0621,OPHN1L | Q9UNA1 | RHG26_HUMAN | 23092 | ENSG00000145819 | Rho GTPase-activating protein 26 | SPROT |
Disease |
Disease |
OMIM id |
Leukemia, juvenile myelomonocytic (JMML) [MIM:607785]: An aggressive pediatric myelodysplastic syndrome/myeloproliferative disorder characterized by malignant transformation in the hematopoietic stem cell compartment with proliferation of differentiated progeny. Patients have splenomegaly, enlarged lymph nodes, rashes, and hemorrhages. Note=The gene represented in this entry is involved in disease pathogenesis. A chromosomal translocation t(511)(q31q23) with MLL has been found in leukemic cells from JMML patients, also carrying inactivating mutations on the second allele (PubMed:10908648). |
607785 |