Please wait while page loads....
Details of CREBBP gene in Homo sapiens
Disease |
|---|
| Disease |
OMIM id |
| Note=Chromosomal aberrations involving CREBBP may be a cause of acute myeloid leukemias. Translocation t(816)(p11p13) with KAT6A translocation t(1116)(q23p13.3) with MLL/HRX translocation t(1016)(q22p13) with KAT6B. KAT6A-CREBBP may induce leukemia by inhibiting RUNX1-mediated transcription. |
--- |
Rubinstein-Taybi syndrome 1 (RSTS1) [MIM:180849]: A disorder characterized by craniofacial abnormalities, postnatal growth deficiency, broad thumbs, broad big toes, mental retardation and a propensity for development of malignancies. Note=The disease is caused by mutations affecting the gene represented in this entry. |
180849 |
Orthologs in other species |
|---|
| M. musculus |
D. melonogaster |
C. elegans |
S. purpuratus |
| Crebbp | nej | cbp-1 | Sp-Cbp |
