Metazoan complexes |
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Emili & Marcotte labs |
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Details of aap-1 gene in Caenorhabditis elegans
IDs | |||||||||
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Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
| aap-1 | --- | Q9N597 | --- | --- | WBGene00000001 | Y110A7A.10 | aap-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p50/p55 adaptor/regulatory subunit AAP-1 negatively regulates lifespan and dauer development, and likely functions as the sole adaptor subunit for the AGE-1/p110 PI3K catalytic subunit to which it binds in vitro although AAP-1 potentiates insulin-like signaling, it is not absolutely required for insulin-like signaling under most conditions. | WORMBASE |
Orthologs in other species | |||||||||
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H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
PIK3R3 | Pik3r3 | Pi3K21B | Sp-Pik3r1... | PIK3R1 | Pik3r1 | Pi3K21B | Sp-Pik3r1... | PIK3R2 | Pik3r2 | Pi3K21B | Sp-Pik3r1... |