Metazoan Gene Interaction Project

	Metazoan complexes
	Emili & Marcotte labs

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IDs
Link outs	Gene Name	Alias	Uniprot ID	SwissProt ID	NCBI gene ID	W.Base gene ID	W.Base accession	Description	Source
	pab-2	---	Q19581	---	181473	---	F18H3.3	Protein PAB-2, isoform a [Source:RefSeq peptide Acc:NP_510260]	ENSEMBL

Orthologs in other species
H. sapiens	M. musculus	D. melonogaster	S. purpuratus
PABPC1	Pabpc1	pAbp	Sp-Pabpc1
PABPC3	---	pAbp	Sp-Pabpc1
PABPC4	Pabpc4	pAbp	Sp-Pabpc1
PABPC1L	ENSMUSG00000054582	pAbp	Sp-Pabpc1

Conserved gene 1	Conserved gene 2	Conserved score	C. elegans gene 1	C. elegans gene 2	Complex ID	Corum	BioGrid	IRefWeb	Novelty
PABPC1	EEF1G	0.084677749	pab-1 pab-2	eef-1G eef-1G	cpx968	no	no	no	Novel
PABPC1	G3BP2	0.217213724	pab-2 pab-1	K08F4.2 K08F4.2	cpx33	no	no	no	Novel
PABPC4	G3BP2	0.423046808	pab-2 pab-1	K08F4.2 K08F4.2	cpx33	no	no	no	Novel
PABPC1	HSPA8	0.091607414	pab-2 pab-1	hsp-1 hsp-1	cpx884	yes	yes	yes	Known
PABPC1	MSI2	0.120761453	pab-2 pab-1	msi-1 msi-1	cpx33	no	no	no	Novel
PABPC4	MSI2	0.149181389	pab-2 pab-1	msi-1 msi-1	cpx33	no	no	no	Novel
EIF4G3	PABPC1	0.609437345	ifg-1 ifg-1	pab-2 pab-1	cpx33	no	yes	yes	Known
EIF4E	PABPC1	0.755837943	ife-3 ife-3	pab-1 pab-2	cpx33	no	yes	yes	Known
ALYREF	PABPC1	0.537629762	aly-3 aly-2 aly-1 aly-3	pab-2 pab-1 pab-1 pab-1	cpx33	yes	yes	yes	Known
PABPC4	PABPC1	0.067449439	pab-1 pab-2 pab-1	pab-2 pab-2 pab-1	cpx33	no	no	no	Novel
EIF4G1	PABPC1	0.585665806	ifg-1 ifg-1	pab-2 pab-1	cpx33	yes	yes	yes	Known
EEF1A1	PABPC1	0.162542531	eef-1A.2:eef-1A.1	pab-1:pab-2	cpx830	no	yes	yes	Known
EIF4E	PABPC3	0.561715002	ife-3 ife-3	pab-1 pab-2	cpx101	no	yes	yes	Known
EIF4G1	PABPC4	0.425708957	ifg-1 ifg-1	pab-2 pab-1	cpx33	no	yes	no	Known
ALYREF	PABPC4	0.381155345	aly-3 aly-2 aly-1 aly-3	pab-2 pab-1 pab-1 pab-1	cpx33	no	yes	yes	Known
EIF4G3	PABPC4	0.213339551	ifg-1 ifg-1	pab-2 pab-1	cpx33	no	yes	no	Known
EIF4E	PABPC4	0.58125644	ife-3 ife-3	pab-1 pab-2	cpx33	no	yes	yes	Known
PABPC1	RPL7A	0.148285506	pab-2 pab-1	rpl-7A rpl-7A	cpx968	no	no	no	Novel
PABPC1	RPLP2	0.091913898	pab-1 pab-2	rpa-2 rpa-2	cpx882	no	no	no	Novel
PABPC1	RPS16	0.16168475	pab-2 pab-1	rps-16 rps-16	cpx831	no	yes	no	Known
PABPC1	RPS4X	0.120396798	pab-1 pab-2	rps-4 rps-4	cpx855	no	yes	no	Known
PABPC1	RPS6	0.090744796	pab-2 pab-1	rps-6 rps-6	cpx968	no	no	no	Novel
PABPC1	RPS9	0.064099391	pab-2 pab-1	rps-9 rps-9	cpx943	no	no	no	Novel
PABPC1	RPL17-C18orf32	0.133343622	pab-1 pab-2	rpl-17 rpl-17	cpx968	no	no	no	Novel

Conserved gene 1	Conserved gene 2	Conserved score	C. elegans gene 1	C. elegans gene 2
PABPC1	RPLP0	0.140755505	pab-1, pab-2	rpa-0
POLE	PABPC4	0.115146248	F33H2.5	pab-1, pab-2
PABPC1	RPL27	0.212599919	pab-1, pab-2	rpl-27
PABPC4	PPT1	0.071463489	pab-1, pab-2	ppt-1
SART1	PABPC4	0.094527748	F19F10.9	pab-1, pab-2
RPL7	PABPC4	0.104099291	rpl-7	pab-1, pab-2
PABPC1	PRPF8	0.107822923	pab-1, pab-2	prp-8
PABPC1	PAPOLA	0.073222319	pab-1, pab-2	pap-1, F43G6.5
PABPC4	ECH1	0.073568894	pab-1, pab-2	Y25C1A.13, F58A6.1
PABPC1	RPL27A	0.124768678	pab-1, pab-2	Y37E3.8
PABPC4	NHP2L1	0.073976684	pab-1, pab-2	M28.5
PABPC3	PEBP1	0.078188792	pab-1, pab-2	F40A3.3
PHGDH	PABPC1	0.070278275	C31C9.2	pab-1, pab-2
BRIX1	PABPC1	0.179323336	K12H4.3	pab-1, pab-2
ATXN2L	PABPC4	0.156810087	atx-2	pab-1, pab-2
RPL5	PABPC4	0.129995294	rpl-5	pab-1, pab-2
RPL35	PABPC1	0.092151076	rpl-35	pab-1, pab-2
PABPC1	RPL10A	0.204181166	pab-1, pab-2	rpl-1
UAP1	PABPC1	0.075627257	C36A4.4	pab-1, pab-2
PABPC1	PCBP1	0.166575156	pab-1, pab-2	pes-4
POLE	PABPC1	0.102903224	F33H2.5	pab-1, pab-2
PABPC1	RPL3	0.128827417	pab-1, pab-2	rpl-3
PABPC1	PCBP2	0.093586438	pab-1, pab-2	pes-4
PABPC1	PAPOLB	0.096372954	pab-1, pab-2	pap-1, F43G6.5
PABPC1	RPL6	0.207489794	pab-1, pab-2	rpl-6
PABPC4	RPL27	0.082968236	pab-1, pab-2	rpl-27
SOD1	PABPC4	0.107633485	sod-1	pab-1, pab-2
PABPC1	CSTF2	0.091060874	pab-1, pab-2	cpf-2
DDX39A	PABPC1	0.088232188	hel-1	pab-1, pab-2
ATXN2	PABPC1	0.439344583	atx-2	pab-1, pab-2
PABPC4	RPL18A	0.297194646	pab-1, pab-2	rpl-20
DDX39B	PABPC1	0.10314664	hel-1	pab-1, pab-2
DHX15	PABPC4	0.098097676	F56D2.6	pab-1, pab-2
PABPC1	RPL14	0.132084965	pab-1, pab-2	rpl-14
PABPC3	NHP2L1	0.070388986	pab-1, pab-2	M28.5
PABPC1	PDCD6	0.125844705	pab-1, pab-2	M04F3.4
PABPC1	HNRNPR	0.752399167	pab-1, pab-2	hrp-2
ATXN2	PABPC4	0.188834436	atx-2	pab-1, pab-2
PABPC4	FBL	0.074923596	pab-1, pab-2	fib-1
RPL18	PABPC4	0.096073541	rpl-18	pab-1, pab-2
BRIX1	PABPC3	0.149711905	K12H4.3	pab-1, pab-2
PABPC1	G3BP1	0.170562047	pab-1, pab-2	K08F4.2
CNBP	PABPC4	0.088858952	K08D12.3	pab-1, pab-2
PABPC4	RPL15	0.179490858	pab-1, pab-2	rpl-15
PABPC1	RPS3A	0.073973361	pab-1, pab-2	rps-1
GSPT1	PABPC1	0.154301714	erfa-3	pab-1, pab-2
PABPC1	RPL13	0.080385403	pab-1, pab-2	rpl-13
IMPA2	PABPC4	0.08856715	ttx-7	pab-1, pab-2
PABPC1	SYNCRIP	0.640726354	pab-1, pab-2	hrp-2
WDR1	PABPC4	0.08841711	aipl-1, unc-78	pab-1, pab-2
PABPC1	RPL18A	0.199258129	pab-1, pab-2	rpl-20
PABPC4	CSE1L	0.082919624	pab-1, pab-2	xpo-2
PABPC4	RPL3L	0.070230094	pab-1, pab-2	rpl-3
CSTF3	PABPC3	0.120628876	suf-1	pab-1, pab-2
RPL5	PABPC1	0.216576484	rpl-5	pab-1, pab-2
PABPC1	RPL11	0.104426517	pab-1, pab-2	rpl-11.2, rpl-11.1
PABPC4	PDCD6	0.090105287	pab-1, pab-2	M04F3.4
PABPC1	MIF	0.084514892	pab-1, pab-2	mif-1
BRIX1	PABPC4	0.08200183	K12H4.3	pab-1, pab-2
PABPC1	FDPS	0.071011425	pab-1, pab-2	fdps-1
RPL18	PABPC1	0.170172903	rpl-18	pab-1, pab-2
PABPC4	G3BP1	0.128223288	pab-1, pab-2	K08F4.2
PABPC4	RPL8	0.094437863	pab-1, pab-2	rpl-8
PFAS	PABPC1	0.079482542	F10F2.2	pab-1, pab-2
ATXN2L	PABPC1	0.093067968	atx-2	pab-1, pab-2
PABPC4	RPS9	0.086141002	pab-1, pab-2	rps-9
PABPC1	KIN	0.110114934	pab-1, pab-2	Y52B11A.9
RPL7	PABPC1	0.235780508	rpl-7	pab-1, pab-2
SKIV2L2	PABPC1	0.112131198	mtr-4	pab-1, pab-2
PABPC1	RPL37A	0.195886737	pab-1, pab-2	rpl-43
PABPC1	RPL4	0.102297958	pab-1, pab-2	rpl-4
PABPC3	PAN3	0.151162028	pab-1, pab-2	ZK632.7
PABPC4	APRT	0.083995042	pab-1, pab-2	T19B4.3
RAE1	PABPC4	0.162814118	npp-17	pab-1, pab-2
PABPC4	PPA1	0.076554847	pab-1, pab-2	pyp-1
CSTF3	PABPC1	0.108966899	suf-1	pab-1, pab-2
CNBP	PABPC3	0.126873559	K08D12.3	pab-1, pab-2
PABPC4	RPS3A	0.073246311	pab-1, pab-2	rps-1
SKIV2L2	PABPC4	0.084738049	mtr-4	pab-1, pab-2
PABPC3	PAPOLA	0.089800051	pab-1, pab-2	pap-1, F43G6.5
DHX15	PABPC1	0.169007424	F56D2.6	pab-1, pab-2
SART1	PABPC1	0.142600009	F19F10.9	pab-1, pab-2
GSPT1	PABPC4	0.085709168	erfa-3	pab-1, pab-2
RPL13A	PABPC4	0.148233913	rpl-16	pab-1, pab-2
DDX39A	PABPC4	0.090837192	hel-1	pab-1, pab-2
DDX39B	PABPC4	0.089586699	hel-1	pab-1, pab-2
RAE1	PABPC1	0.190491146	npp-17	pab-1, pab-2
SOD1	PABPC3	0.079614581	sod-1	pab-1, pab-2
PHGDH	PABPC4	0.102627228	C31C9.2	pab-1, pab-2
PABPC1	NHP2L1	0.107027589	pab-1, pab-2	M28.5
PABPC1	RPS8	0.12088211	pab-1, pab-2	rps-8
PABPC1	RPL15	0.237409168	pab-1, pab-2	rpl-15
RPL13A	PABPC1	0.251261967	rpl-16	pab-1, pab-2
TMOD2	PABPC3	0.072283397	unc-94	pab-1, pab-2

Metazoan complexes

Emili & Marcotte labs

Details of pab-2 gene in Caenorhabditis elegans

IDs

Phenotypes

Orthologs in other species