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Details of chc-1 gene in Caenorhabditis elegans
IDs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Link outs | Gene Name | Alias | Uniprot ID | SwissProt ID | NCBI gene ID | W.Base gene ID | W.Base accession | Description | Source |
|
| chc-1 | --- | P34574 | CLH_CAEEL | 176434 | WBGene00011867 | T20G5.1 | Probable clathrin heavy chain 1 | SPROT |
Phenotypes
accumulated germline cell corpses, adult lethal, apoptosis variant, cleavage furrow initiation defective early emb, diet induced life span variant, diplotene region organization variant, embryonic lethal, endocytic transport variant, germ cell compartment anucleate, germ cell compartment expansion variant, germ cell compartment morphology variant, germ cell compartment multinucleate, germ cell morphology variant, germline nuclear positioning variant, gonad morphology variant, integrity of membranous organelles defective early emb, larval lethal, life span variant, lysosome-related organelle morphology variant, maternal sterile, oocyte number decreased, oocytes lack nucleus, organism starvation response variant, pattern of transgene expression variant, protein degradation variant, protein subcellular localization variant, RAB-11 recycling endosome morphology variant, receptor mediated endocytosis defective, reduced brood size, shortened life span, slow growth, sterile, transgene expression reduced, transgene subcellular localization variant, uptake of yolk defective.
Orthologs in other species | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| H. sapiens | M. musculus | D. melonogaster | S. purpuratus | ||||||
| BLOC1S1 | Bloc1s1 | blos1 | Sp-Bloc1S1 | CLTC | Cltc | Chc | Sp-Cltc | CLTCL1 | --- | Chc | --- |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
Complex ID | Corum | BioGrid | IRefWeb | Novelty |
|---|---|---|---|---|---|---|---|---|---|
| CLTC | PPP2R1A | 0.182702163 | chc-1 | paa-1 | cpx35 | no | yes | no | Known |
| CLTC | PPP2R1B | 0.372744096 | chc-1 | paa-1 | cpx796 | no | yes | no | Known |
| CLTC | ATP1A1 | 0.435681375 | chc-1 | eat-6 | cpx7 | no | yes | no | Known |
| CLTC | ATP1A2 | 0.243237314 | chc-1 | eat-6 | cpx84 | no | yes | no | Known |
| CLTC | ATP5C1 | 0.187030031 | chc-1 | Y69A2AR.18 | cpx7 | no | yes | no | Known |
| BLOC1S1 | CLTC | 0.238652499 | blos-1 | chc-1 | cpx84 | no | no | no | Novel |
| HSP90B1 | CLTC | 0.376139196 | enpl-1 | chc-1 | cpx7; cpx15 | no | yes | no | Known |
| RAB2A | CLTC | 0.030149543 | unc-108 | chc-1 | cpx7 | no | no | no | Novel |
| SLC25A3 | CLTC | 0.248787844 | F01G4.6 | chc-1 | cpx15; cpx20; cpx35 | no | yes | no | Known |
| CLTA | CLTC | 1 | clic-1 | chc-1 | cpx84 | no | yes | no | Known |
| SSR1 | CLTC | 0.053800691 | trap-1 | chc-1 | cpx20 | no | no | no | Novel |
| EHD1 | CLTC | 0.222709523 | rme-1 | chc-1 | cpx56 | no | yes | no | Known |
| UQCRC2 | CLTC | 0.981072736 | ucr-2.2 ucr-2.1 ucr-2.3 | chc-1 chc-1 chc-1 | cpx7; cpx20; cpx35; cpx15 | no | yes | no | Known |
| CYC1 | CLTC | 0.17235739 | cyc-1 | chc-1 | cpx20 | no | no | no | Novel |
| CANX | CLTC | 0.174807183 | cnx-1 | chc-1 | cpx20; cpx35; cpx7; cpx15 | no | no | no | Novel |
| TECR | CLTC | 0.626388945 | art-1 | chc-1 | cpx56; cpx7; cpx15 | no | yes | no | Known |
| JAGN1 | CLTC | 0.042041157 | K05C4.2 | chc-1 | cpx56 | no | no | no | Novel |
| RANBP6 | CLTC | 0.154945993 | imb-3 | chc-1 | cpx84 | no | yes | no | Known |
| TOMM22 | CLTC | 0.231345993 | tomm-22 | chc-1 | cpx56 | no | no | no | Novel |
| ZMPSTE24 | CLTC | 0.121712245 | fce-1 | chc-1 | cpx84 | no | no | no | Novel |
| CLTB | CLTCL1 | 0.308357474 | clic-1 | chc-1 | cpx503 | no | yes | no | Known |
| CLTC | MT-CO2 | 0.259653278 | chc-1 | cox-2 | cpx20; cpx7 | no | no | no | Novel |
| CLTC | TUFM | 0.148915577 | chc-1 | tufm-1 | cpx20 | no | yes | no | Known |
| CLTC | DDOST | 0.328276947 | chc-1 | T09A5.11 | cpx7; cpx56 | no | yes | no | Known |
| CLTC | RPN1 | 0.863634511 | chc-1 | ribo-1 | cpx15; cpx7 | no | yes | no | Known |
| CLTC | CCT3 | 0.649175109 | chc-1 | cct-3 | cpx35 | no | yes | no | Known |
| CLTC | CCT8 | 0.063251997 | chc-1 | cct-8 | cpx947 | no | yes | no | Known |
| CLTCL1 | CCT6B | 0.278288707 | chc-1 | cct-6 | cpx220 | no | yes | no | Known |
| CLTC | CCT6A | 0.083622756 | chc-1 | cct-6 | cpx899 | no | yes | no | Known |
| Conserved gene 1 |
Conserved gene 2 |
Conserved score |
C. elegans gene 1 |
C. elegans gene 2 |
|---|---|---|---|---|
| CLTCL1 | ATP1A1 | 0.178854566 | chc-1 | eat-6 |
| CLTC | PHB | 0.192423649 | chc-1 | phb-1 |
| VDAC1 | CLTC | 0.090976513 | R05G6.7 | chc-1 |
| CLTC | PHB2 | 0.119577887 | chc-1 | phb-2 |
| VDAC2 | CLTC | 0.127763015 | R05G6.7 | chc-1 |
| CLTCL1 | IDH3A | 0.693039638 | chc-1 | F43G9.1 |
| CLTC | EIF6 | 0.102775193 | chc-1 | eif-6 |
| NDUFS1 | CLTC | 0.146255945 | nuo-5 | chc-1 |
| CLTA | CLTCL1 | 0.336641219 | clic-1 | chc-1 |
| NDUFB9 | CLTC | 0.092390566 | C16A3.5 | chc-1 |
| CLTC | TMCO1 | 0.117140368 | chc-1 | F22B5.10 |
| VDAC3 | CLTC | 0.10365501 | R05G6.7 | chc-1 |
| CLTCL1 | PPP2R1A | 0.18773247 | chc-1 | paa-1 |
| MTCH2 | CLTC | 0.100992989 | mtch-1 | chc-1 |
| CAD | CLTC | 0.110145082 | pyr-1 | chc-1 |
| CLTC | CCDC47 | 0.112316574 | chc-1 | ccdc-47 |
| RAB5B | CLTC | 0.078379198 | rab-5 | chc-1 |
| CLTCL1 | EPRS | 0.078039212 | chc-1 | ears-1 |
| IPO5 | CLTC | 0.222707143 | imb-3 | chc-1 |
| CLTC | UQCRQ | 0.100595651 | chc-1 | R07E4.3, F45H10.2 |
| CLTCL1 | AHSA1 | 0.110750593 | chc-1 | C01G10.8 |
| CLTC | ATP1A3 | 0.25029713 | chc-1 | eat-6 |
| CCT6B | CLTC | 0.209586816 | cct-6 | chc-1 |
| SSR3 | CLTC | 0.112476112 | trap-3 | chc-1 |